HOW DOES SAW PALMETTO WORK: A FEW WORDS ABOUT ANDROGENS
Testosterone is the best-known androgen, or male hormone. It is made primarily by the testicles, ovaries, and adrenal glands. Once testosterone is made, it can act locally or enter the bloodstream to travel to all parts of the body. Testosterone can have an influence on a variety of organs including skin, hair, brain, muscles, liver, and heart.
The enzyme 5-alpha-reductase converts testosterone to a more potent androgen known as dihydrotestosterone (DHT). This enzyme is present in a variety of body tissues, but not evenly. Some tissues, such as hair, skin and prostate have an active 5-alpha-reductase enzyme and are able to efficiently convert testosterone into DHT. Other tissues, such as muscle, cannot easily convert testosterone into DHT.
DHT is one of the culprits responsible for prostate gland enlargement, acne, male pattern baldness and, in women, excessive hair growth in unwanted places. There is an inherited enzyme deficiency that occurs in humans which has given us clues on what happens when DHT is not formed. There are reports from the Dominican Republic and Turkey of certain families that have males who have a genetic deficiency. They can't make DHT. Blood studies show low levels of DHT while their blood testosterone levels are high.
All females affected with this condition appear normal. Males have problems: they are born with undefined genitalia, a small penis, and testicles that don't descend. Fortunately for them, at puberty, their blood testosterone levels rise, their penis enlarges and the testicles descend. Even more fortunate is that they have no acne, little hair growth on their bodies, no prostate enlargement, and no receding hairline!
This genetic enzyme deficiency of 5-alpha-reductase, and the subsequent absence of DHT, gives enormous clues to the function of this hormone. It suggests that medicines that block the conversion of testosterone to DHT, or block the influence of DHT on certain tissues such as hair, skin and prostate, may not be such a bad thing after all. Joyce Tanover, M.D., Assistant Professor of Medicine at Emory University School of Medicine in Atlanta, Georgia, says, "It is of interest that at least three of the major effects of DHT in the postpuberal male are in areas that are considered to be undesirable or to lead to a 'disease'; namely, prostate growth, acne, and baldness. It is not surprising that such information has led to a search for effective and specific human 5-alpha-reductase inhibitors. Such compounds might be useful in the treatment of acne, BPH, or male pattern baldness and are potentially without major adverse effects."
Keeping in mind that these are theories, not definite answers, we'll look in more detail at some potential ways on how SP can help reduce prostatic symptoms.
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Men's Health Erectile Dysfunction